St. Petersburg Health & Wellness

Exosomes: The Shining Stars of Regenerative Medicine
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by Les Cole, MD & Kathie Gonzales, ARPN-BC

Exosomes – What are they?

All cells produce and secrete exosomes. Exosomes carry signaling and other molecules to influence cells around them. In Regenerative Medicine “Exosomes” refer to Stem Cell Exosomes. So, when a Stem Cell gets something done, it is through the release of its Exosomes. There is no regeneration without them.

So, why is this important to Regenerative Medicine and You? It is profoundly important because you can get everything done that a Stem Cell will do, but without the problems associated with injecting Stem Cells, of which there are many. In addition, Exosomes work better and much faster than Stem Cells no matter the site of injection.

We utilize Exosomes at St Petersburg Health and Wellness for the greater benefit they provide our patients. Below are listed some of the major differences between Exosomes & Stem Cells:


  • Aren’t alive so don’t die
  • Don’t cause inflammation
  • Go directly to the damage
  • Turn on Your own Stem Cells
  • Make them:
    • More youthful
    • Divide to make more
    • Decrease inflammation
    • Repair damage
    • Replace damaged cells
  • From young placental Stem Cells
  • Are more concentrated
  • Work faster
  • Are safer

Stem Cells

  • Are alive
  • Majority die in several days
    • Or before injected when thawed
    • All dead by ~ 7 days
  • Dead cells cause inflammation
  • Do not replace damaged tissue
  • Don’t have as many Exosomes
  • Don’t all reach damaged areas
  • Must use your own Stem Cells
    • Which are your age
    • FDA Mandated
  • Produce older, fewer Exosomes
  • Only work through Exosomes

The FDA currently regulates both and is very restrictive with Stem Cells. They are placed in 2 completely different categories with Stem Cells having significantly more regulation. The age of Exosomes is critical to their effect and Your outcome. The younger the Exosomes are the better. The older they are (i.e. from your own Stem Cells, which are the only kind of Stem Cells the FDA allows) the less effective they are.

Exosomes are used for Esthetics like Facelifts and Hair Growth to Joint damage/disease, Metabolic Disease including Obesity and Diabetes, Autoimmunity, Cardiovascular disease including Heart Attack, Heart Failure, and Stroke, Neurologic disease, Gastrointestinal disease, Eye disease, Trauma including Burns and many, many more. And they are being used for Anti-Aging and Preventive Medicines from the inside out.

As you can see, Exosomes are how Stem Cells work, so with the above information, which will You choose when it is time? Call St. Petersburg Health & Wellness to learn more, find out Seminar dates, to see if we can help you or to make an appointment. If your New Year’s resolutions include Health, Fitness, Exercise, Weight Loss, Exosomes are a great way for you to kick-start your process and improve your over-all health at the same time.

Article History


Meet Our

Providers & Staff

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Doctor of Functional & Metabolic Medicine

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Kathie Gonzales, ARNP

Family Nurse Practitioner

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Jayla Blair

Medical Assistant
Patient Care Coordinator

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June Drennon

Clinical Thermographer