St. Petersburg Health & Wellness

Age Gracefully, Naturally
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Natural Hormone Replacement & Peptides 

By Les Cole, MD & Kathie Gonzales, ARNP-BC

Hormone balance is of critical importance in how we feel, affecting our mood, sleep, energy & sex drive, natural Hormone Replacement Therapy (HRT) is an individualized treatment that can alleviate many, if not all, symptoms can improve cardiovascular health and decrease heart joint health.  HRT comes in multiple forms: topical creams and patches; oral troches; injectables and pellets.   Pellet therapy has been successfully used in the U.S. and Europe since 1938.  It requires a small incision in the upper buttocks or lower abdomen where the small pellet cylinder is placed under the skin in the subcutaneous tissue.  Pellets provide for stable hormone levels, not dependent on remembering when to take or proper application.  The hormone levels typically last three to six months.

Hormone Replacement Therapy has now expanded into the future of medicine. We are now able to replace over 60 hormones called Peptides that decrease with age. Until recently we have only been able to replace sex hormones which have been a boon for improving symptoms, quality of life, treating disease, healing sexual tissues and function, and extending health-span & lifespan.

You may have heard of several peptide hormones, one of which is Growth Hormone. This has been used by some anti-aging practitioners but is frowned upon by the FDA & has negative long term side effects. Recent research, however, has opened up a whole knowledge base of specific and safe Peptide Hormones now available to you! These peptides serve many important functions in your body and, just like with your sex hormones, they decrease as you age.

And, just like with the loss of your sex hormones, the loss of these peptide hormones accelerates your aging process by both decreasing your health-span and your lifespan. A simple yet elegant experiment demonstrates this. A young mouse and an old mouse were sewn together so they shared a blood supply and put on an immunosuppressant so they would not reject each other. The older mouse made the younger mouse older and the younger mouse made the older mouse younger. The younger mouse’s peptides were what caused the older mouse to grow younger and the older mouse’s lack of peptide production could not sustain the younger mouse’s youth!

There are now over 60 peptides available that can help with a multitude of symptoms or just plain make you feel better. Some of the benefits associated with just 2 of these peptides are:

  • Weight loss
  • Sleep
  • Bone density
  • Muscle mass
  • Immune function
  • Libido
  • Sexual function
  • Mood
  • Motivation
  • Memory
  • Skin & Hair
  • Energy & Endurance
  • Memory
  • Cognition
  • And this is just a partial list

For more information, call St. Petersburg Health & Wellness 727-202-6807.  Located at 2100 Dr. MLK Jr. St. N, St. Pete.   The health of our patients and staff are protected with two REME-HALO devices which kill 99-plus percent of all infectious agents (viruses, bacteria, etc.) in the air and on surfaces throughout the facility.

Article History


Meet Our

Providers & Staff

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Doctor of Functional & Metabolic Medicine

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Kathie Gonzales, ARNP

Family Nurse Practitioner

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Jayla Blair

Medical Assistant
Patient Care Coordinator

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June Drennon

Clinical Thermographer