Premature coronary artery disease (CAD) occurs at an earlier age than in the most people. In a study of men under 45 years of age with CAD, testosterone levels were measured and compared to the levels found in 45 year old men without CAD. At the same time a variety of other risk factors for  CAD were identified and compared between the 2 groups. The findings identified hyperlipidemia  (high cholesterol), cigarette smoking and low free testosterone levels as independent predictors of premature CAD. In this study, free testosterone levels below 17.3 pg/ml were associated with a 330% increased risk of premature coronary artery disease.

Andropause  occurs between the ages of 40 to 50 and sometimes younger and can be associated with a number of symptoms. Bio-identical testosterone replacement can return testosterone levels to normal.

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